Effect of duration of diabetic in glutamic acid decarboxylase autoantibodies and HbA1c in children with T1DM

Background: a metabolic condition characterized by failure in the metabolism of proteins, lipids, and carbohydrates that is brought on problems with insulin production. When multiple autoantibodies, such as those against glutamic acid decarboxylase, are present different antigens, type 1 diabetes present. Objective: To estimate Glutamic Acid Decarboxylase Autoantibodies assessment HbA1c DM. Methods: 40 children participated, while 10 kids control group had blood sugar levels were normal. for each participant measured part quantitative ELISA test identification circulating autoantibodies decarboxylase human serum. Results: All pathological samples showed an increase concentration Anti-GAD compared to control. Samples patients 5 years or more decrease less than five years, but was not significant Conclusion: There positive association between duration Diabetes Mellitus